Titans vs. Colts odds, line, spread: Thursday Night Football picks, predictions from model on 112-74 roll

The Tennessee Titans have been involved in tight contests this season, with six of their eight games being decided by fewer than eight points. Tennessee has gone 5-1 in those games, with three of the victories coming by three points or fewer and the lone loss being by a field goal. The Titans hope to come away with a more comfortable win when they host the AFC South-rival Indianapolis Colts on Thursday Night Football. Kickoff from Nissan Stadium in Nashville is scheduled for 8:20 p.m. ET.

Tennessee (6-2) had a big lead in the fourth quarter last Sunday, but gave up two late touchdowns before coming away with a 24-17 home win over Chicago. Indianapolis (5-3) posted back-to-back victories to pull even with the Titans for first place in the division before falling 24-10 to Baltimore at home last week. Thursday Night Football is a pick’em in the latest Titans vs. Colts odds from William Hill Sportsbook, while the over-under is 48.5. Before locking in any Colts vs. Titans picks, make sure you see the latest Thursday Night Football predictions from SportsLine’s proven projection model.

The model, which simulates every NFL game 10,000 times, is up over $7,600 for $100 players on top-rated NFL picks since its inception five-plus years ago. It’s off to a strong 16-9 roll on top-rated NFL picks this season. The model enters Week 10 on an incredible 112-74 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Colts vs. Titans. You can visit SportsLine now to see the picks. Here are the NFL odds from William Hill and trends for Titans vs. Colts:

Titans vs. Colts spread: PKTitans vs. Colts over-under: 48.5 pointsTitans vs. Colts money line: Tennessee -105, Indianapolis -115TEN: Titans are 2-5 against the spread in their last seven games as favoritesIND: Over has hit in three of last four Colts gamesWhy the Titans can cover

Ryan Tannehill completed only 10 of his 21 pass attempts in the victory over the Bears, but two were for touchdowns. The 32-year-old has been far more accurate against Indianapolis during his career, completing 66.9 percent of his 157 tosses in five meetings.

Tennessee has struggled against the pass in 2020, ranking 27th with 275 yards allowed per game. But the defense has received a strong effort from tackle Jeffery Simmons, who was named AFC Defensive Player of the Week after his performance against Chicago. The 19th overall pick in the 2019 NFL Draft, Simmons recorded three tackles, recovered one fumble and forced another that was returned 63 yards for a touchdown by cornerback Desmond King II.

Why the Colts can cover

Philip Rivers has thrown only 10 touchdown passes and seven interceptions in his first season with Indianapolis but has a successful history against the Titans franchise. In nine career meetings, the 38-year-old completed 70.4 percent of his pass attempts while leading the Chargers to seven victories.

Indianapolis hopes to have wide receiver T.Y. Hilton on the field after he missed the loss to the Ravens with a groin injury. Hilton, who has been a full participant in practice this week, has hauled in 61 passes for 941 yards and five TDs in 15 career games against Tennessee.

How to make Titans vs. Colts picks

SportsLine’s model is leaning under. In fact, it’s calling for 47 total points. It also says one side of the spread hits well over 50 percent of the time. You can only get the pick here.

So who wins Colts vs. Titans on Thursday Night Football? And which side of the spread hits well over 50 percent the time? Visit SportsLine now to see which side of the Colts vs. Titans spread to jump on, all from the advanced model that is up more than $7,600 on its top-rated NFL picks, and find out.

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